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Michael Deem is the John W. Cox Professor of Biochemical and Genetic Engineering and Professor of Physics & Astronomy at Rice University in Houston, Texas. He is known for his work in parallel tempering and proposals to improve vaccine development by estimating the antigenic "distance" for any two samples of virus. He is listed on Technology Review 35 (TR100), a list by Technology Review for remarkable innovators under the age of 35.

Deem received his B.S. in Chemical Engineering from the California Institute of Technology in 1991 and his Ph.D. in Chemical Engineering from the University of California at Berkeley in 1994.

Education
Dr. Deem went to B.S., California Institute of Technology in 1991, then gained his Ph.D. at University of California at Berkeley in 1994, and finally got his Postdoctoral Fellow at Harvard University from 1995 to 1996.

Honors and awards
Dr. Deem's research in zeolites has led him to the following awards.


 * National Science Foundation CAREER Awards, 1997
 * Top 100 Young Innovator
 * MIT Technology Review, 1999
 * Alfred P. Sloan Fellow, 2000
 * Camille Dreyfus Teacher-Scholar Award,2002
 * Allan P. Colburn Award, 2004
 * Vaughan Lectureship
 * California Institute of Technology, 2007
 * Professional Progress Award of the AIChE, 2010
 * O'Donnell Award from the Academy of Medicine
 * Engineering and Science of Texas, 2012

Publications
Michael W Deem has, along with many other co-authors, published many works about his field of science


 * ``The Physicist's Guide to One of Biotechnology's Hottest New Topics: CRISPR-Cas,``
 * ``Predicting influenza H3N2 vaccine effectiveness from evolution of the dominant epitope,``
 * ``The standard genetic code facilitates exploration of the space of functional nucleotide sequences,``
 * ``Analysis of hierarchical organization in gene expression networks reveals underlying principles of collective tumor cell dissemination and metastatic aggressiveness of inflammatory breast cancer,``
 * ``Single Molecule Sequencing of Cell-free DNA from Maternal Plasma for Noninvasive Trisomy Detection,``
 * ``Modularity of the Metabolic Gene Network as a Prognostic Biomarker for Hepatocellular Carcinoma,``
 * ``Resequencing the Escherichia coli genome by GenoCare single molecule sequencing platform,``
 * ``Single molecule sequencing of M13 virus genome without amplification,``
 * ``How the other half lives: CRISPR-Cas's influence on bacteriophages,``
 * ``Static and Dynamic Measures of Human Brain Connectivity Predict Complementary Aspects of Human Cognitive Performance,``
 * ``Brain Modularity Mediates the Relation of Cognitive Performance to Task Complexity,``
 * ``Enantiomerically Enriched, Polycrystalline Molecular Sieves,``
 * ``A Pareto Algorithm for Efficient De Novo Design of Multi-Functional Molecules,``
 * ``A Non-Classical Phase Diagram for Virus-Bacterial Co-Evolution Mediated by CRISPR,``
 * ``Single Molecule Targeted Sequencing for Cancer Gene Mutation Detection,``
 * ``Modular Knowledge Systems Accelerate Human Migration in Asymmetric Random Environments,``
 * ``Template-Framework Interactions in Tetraethylammonium Directed Zeolite Synthesis,``
 * ``T Cell Repertoire Diversity Is Decreased in Type 1 Diabetes,``
 * ``Prediction of Influenza B Vaccine Effectiveness from Sequence Data,``
 * ``Influenza Evolution and H3N2 Vaccine Effectiveness, with Application to the 2014/2015 Season,``
 * ``Synthesis of Germanosilicate Molecular Sieves from Mono- and Di-Quaternary Ammonium OSDAs Constructed from Benzyl Imidazolium Derivatives: Stabilization of Large Micropore Volumes Including New Molecular Sieve CIT-13,``
 * ``Computationally-Guided Synthesis of SSZ-52, a Zeolite for Engine Exhaust Clean-up,``
 * ``Facile Synthesis and Catalysis of Pure-Silica and Heteroatom LTA,``
 * ``Computer-Aided Search for Materials to Store Natural Gas for Vehicles,``
 * ``Understanding the Earth and its Resources,`` 2015, doi:10.3389/frym.2015.00011 (Reprint).
 * ``Computationally-Guided Synthesis of the 8-Ring Zeolite AEI,``
 * ``In Silico Prediction of MOFs with High Deliverable Capacity or Internal Surface Area,``
 * ``The Materials Genome in Action: Identifying the Performance Limits for Methane Storage,``
 * ``Modularity Enhances the Rate of Evolution in a Rugged Fitness Landscape,``
 * ``Hierarchy in Gene Expression is Predictive of Risk, Progression, and Outcome in Adult Acute Myeloid Leukemia,``
 * ``Discovery of Optimal Zeolites for Challenging Separations and Chemical Transformations using Predictive Materials Modeling,``
 * ``Quasispecies Theory for Evolution of Modularity,``
 * ``In Silico Discovery of High Deliverable Capacity Metal-Organic Frameworks,``
 * ``Development of Modularity in the Neural Activity of Children's Brains,``
 * ``Preferential Location of Ge in the UTL and IPC-2a Zeolites,``
 * ``Why Zeolites Have So Few 7-Membered Rings,``
 * ``Synthesis of a Specified, Silica Molecular Sieve using Computationally Predicted Organic Structure Directing Agents,``
 * ``Modularity, Plasticity, and Development of Brain Function,``
 * ``Evolution: Life has Evolved to Evolve,``
 * ``Computational Prediction of Chemically-Synthesizable Organic Structure Directing Agents for Zeolites,``
 * ``Adsorption of Glucose into Zeolite Beta from Aqueous Solution,``
 * ``Physical Model of the Immune Response of Bacteria Against Bacteriophage Through the Adaptive CRISPR-Cas Immune System,``
 * ``Hierarchy of Gene Expression Data is Predictive of Future Breast Cancer Outcome,``
 * ``Prediction of Heart Rate Response to Conclusion of Spontaneous Breathing Trial by Fluctuation Dissipation Theory,``
 * ``Evolutionary Processes in Finite Populations,``
 * ``Multicanonical Molecular Dynamics by Variable-Temperature Thermostats and Variable-Pressure Barostats,``
 * ``Statistical Mechanics of Modularity and Horizontal Gene Transfer,``
 * ``In Silico Screening of Carbon Capture Materials,``
 * ``A Multi-Scale Model for Correlation in B Cell VDJ Usage of Zebrafish,``
 * ``Evolution of H3N2 Influenza Virus in a Guinea Pig Model,``
 * ``Quantifying Selection and Diversity in Viruses by Entropy Methods, with Application to the Hemagglutinin of H3N2 Influenza,``
 * ``Predicting Fixation Tendencies of the H3N2 Influenza Virus by Free Energy Calculation,``
 * ``A Database of New Zeolite-Like Materials,``
 * ``The Emergence of Modularity in Biological Systems,``
 * ``Statistical Mechanics of Biological Modularity,``
 * ``Selective Pressure to Increase Charge in Immunodominant Epitopes of H3 Hemagglutinin Influenza Protein,``
 * ``A Novel Sequence-Based Antigenic Distance Measure for H1N1, with Application to Vaccine Effectiveness and the Selection of Vaccine Strains,``
 * ``Structure and Response in the World Trade Network,``
 * ``Low-Dimensional Clustering Detects Incipient Dominant Influenza Strain Clusters,``
 * ``Heterogeneous Diversity of Spacers within CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats),``
 * ``Theoretical Aspects of Immunity,``
 * ``Quasispecies Theory for Finite Populations,``
 * ``Hierarchical Evolution of Animal Body Plans,``
 * ``Computational Discovery of New Zeolite-Like Materials,``
 * ``The Epitope Regions of H1-Subtype Influenza A, with Application to Vaccine Efficacy,``
 * ``Comment on Ndifon et al, `On the use of hemagglutination-inhibition for influenza surveillance: Surveillance data are predictive of influenza vaccine effectiveness’,``
 * ``Solution of the Crow-Kimura and Eigen Models for Alphabets of Arbitrary Size by Schwinger Spin Coherent States,``
 * ``Dielectric Constant Measurement of Zeolite Powders by Time Domain Reflectometry,``
 * ``Spontaneous Emergence of Modularity in a Model of Evolving Individuals and in Real Networks,``
 * ``Computer-Assisted Vaccine Design,``
 * ``Statistical Mechanics of the Immune Response to Vaccines,``
 * ``Predicting Clinical Physiology: A Markov Chain Model of Heart Rate Recovery After Spontaneous Breathing Trials in Mechanically Ventilated Patients,``
 * ``Quasispecies Theory for Horizontal Gene Transfer and Recombination,``
 * ``Synthesis and Monte Carlo Structure Determination of SSZ-77: A New Zeolite Topology,``
 * ``Amino Acid Alphabet Size in Protein Evolution Experiments: Better to Search a Small Library Thoroughly or a Large Library Sparsely?``
 * ``Monte Carlo Simulations,``
 * ``Spontaneous Emergence of Modularity in a Model of Evolving Individuals,``
 * ``Phase Diagrams of Quasispecies Theory with Recombination and Horizontal Gene Transfer,``
 * ``Mathematical Adventures in Biology,``
 * ``Schwinger Boson Formulation and Solution of the Crow-Kimura and Eigen Models of Quasispecies Theory,``
 * ``Physical Theory of the Competition that Allows HIV to Escape from the Immune System,``
 * ``Mechanical and Dielectric Properties of Pure-Silica-Zeolites as Low-k Materials,``
 * ``A Theory of Multi-Site Vaccination for Cancer,``
 * ``Evolutionary Design in Biological Physics and Materials Science,``
 * ``Toward a Database of Hypothetical Zeolite Structures,``
 * ``Quantifying Influenza Vaccine Efficacy and Antigenic Distance,``
 * ``Quasispecies Theory for Multiple-Peak Fitness Landscapes,``
 * ``Monte Carlo Simulations of the Homopolypeptide Pair Potential of Mean Force,``
 * ``Sculpting the Immunological Response to Dengue Fever by Polytopic Vaccination,``
 * ``Localization and Glassy Dynamics in the Immune System,``
 * ``Entropy, Disease, and New Opportunities for Chemical Engineering Research,``
 * ``Parallel Tempering: Theory, Applications, and New Perspectives,``
 * ``Book Review: Introduction to Mathematical Methods in Bioinformatics,``
 * ``Glassy Dynamics in the Adaptive Immune Response Prevents Autoimmune Disease,``
 * ``Markov Chains of Infinite Order and Asymptotic Satisfaction of Balance: Application to the Adaptive Integration Method,``
 * ``Complexity in the Immune System,``
 * ``Length, Protein-Protein Interactions, and Complexity,``
 * ``Epitope Analysis for Influenza Vaccine Design,``
 * ``Modulation of Base Specific Mutation and Recombination Rates Enables Functional Adaptation within the Context of the Genetic Code,``
 * ``Evolvability is a Selectable Trait,``
 * ``Correlations in the T Cell Response to Altered Peptide Ligands,``
 * ``Optimal Allocation of Replicas to Processors in Parallel Tempering Simulations,``
 * ``Microarray and EST Database Estimates of mRNA Expression Levels Differ: The Protein Length versus Expression Curve for C. elegans,``
 * ``Complexity in the Immune System: New Opportunities for Chemical Engineering Research,``
 * ``Two-Dimensional Diffusion in the Presence of Topological Disorder,``
 * ``A Statistical Theory of Isotropic Turbulence Well-Defined within the Context of the epsilon Expansion,``
 * ``A Statistical Mechanics Study of Ring Size, Ring Shape, and the Relation to Pores Found in Zeolites,``
 * ``Sequence Space Localization in the Immune System Response to Vaccination and Disease,``
 * ``The Monte Carlo Approach to Library Design and Redesign,``