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Professor Alison Holmes is a professor of infectious diseases at Imperial College London. She is also a fellow of the Academy of Medical Sciences. She is the director of the National Institute of Health Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and AMR. Her work within the NHS includes the role of Associate Medical Director, Director of Infection Prevention and Control and she also works as a consultant in infectious diseases

Her career spans both research-based and clinical domains, and has focused on the use of antibiotics, antibiotic resistance (AMR) epidemiology and public health, specifically within an acute care context. Her work on translational infection has been cited in the UK's AMR strategy. She has twice been called to the House of Commons Science and Technology select committee as an expert witness. Professor Holmes is a member of the European Committee on Infection Control and serves on the European Center for Disease Prevention and Control Committee