User:Mr. Ibrahem/Abatacept

Abatacept, sold under the brand name Orencia, is a medication used to treat rheumatoid arthritis, juvenile idiopathic arthritis, and arthritis associated with psoriasis. It may also be used to prevent graft versus host disease (GVHD). It is usually given by injection into a vein, or under the skin. The dose and frequency depend on a person's body weight.

Common side effects include upper respiratory tract infections, headache, and nausea. Other side effects include anaphylaxis and infection. It is generally not given in pregnancy; birth control is recommended during treatment and for 14 weeks after. It works by attaching to and blocking CD80 and CD86; thereby decreasing the immune activity of T cells.

Abatacept was approved for medical use in the United States in 2005 and Europe in 2007. In the United Kingdom, a typical month of a maintenance dose costs the NHS about £1,500 as of 2021. In the United States this amount costs about 2,600 to 5,200 USD.