User:Mr. Ibrahem/Allopregnanolone

Allopregnanolone is a naturally occurring hormone which is also used as a medication. As a medication, it is known as brexanolone, sold under the brand name Zulresso, and used to treat postpartum depression. It is given by injection into a vein over a 60-hour period under medical supervision.

Common side effects include sleepiness, dry mouth, hot flashes, and loss of consciousness. Other side effects may include suicidal thoughts. Use in pregnancy may harm the baby. It is a neurosteroid and acts as a positive allosteric modulator of the GABAA receptor.

Brexanolone was approved for medical use in the United States in 2019. It is not approved in either Europe or the United Kingdom as of 2022. In the United States a course of medication costs 34,000 USD as of 2019. The long administration time, price, and need for hospitalization, have raised concerns about accessibility.