User:Mr. Ibrahem/Amantadine

Amantadine, sold under the brand name Gocovri among others, is a medication used to treat movement disorders associated with parkinsonism and antipsychotic medication. Other uses may include post herpetic neuralgia and tiredness from multiple sclerosis. It was used to treat and prevent seasonal influenza type A; however, since resistance developed in 2005 such use is no longer recommended. It is taken by mouth.

Amantadine is generally well tolerated. Common side effects include nausea, lightheadedness, and trouble sleeping. Other side effects include swelling of the legs, dry mouth, constipation, neuroleptic malignant syndrome, thoughs of suicide, and hallucinations. Smaller doses are required in people with kidney problems. Use is not recommended during pregnancy or breastfeeding. How it works in movement disorders is unclear, but is believed to be related to increase dopamine effects.

Amantadine was approved for medical use in the United States in 1968. It is available as a generic medication. In the United Kingdom 56 tablets of 100 mg costs the NHS about 36 pounds in 2020. This amount in the United States costs about 23 USD.