User:Mr. Ibrahem/Ambrisentan

Ambrisentan, sold under the brand name Letairis among others, is a medication used for pulmonary hypertension. It improved the ability to exercise and slows worsening. It is not useful in those with pulmonary fibrosis. It is taken by mouth.

Common side effects include swelling, palpitations, headache, and constipation. Other side effects may include anemia, flushing, ringing in the ears, and liver problems. Use in pregnancy may harm the baby. It works by blocking the endothelin receptor, specifically the type A endothelin receptor (ETA).

Ambrisentan was approved for medical use in the United States in 2007 and Europe in 2008. In the United Kingdom it costs the NHS about £1,600 per month. In the United States this amount costs about 5,100 USD as of 2021.