User:Mr. Ibrahem/Anagrelide

Anagrelide, sold under the brand name Agrylin among others, is a medication used to treat high platelets in essential thrombocytosis or other myeloproliferative disorders. It is used when other treatments are not effective or tolerated. It is taken by mouth.

Common side effects may include headache, palpitations, diarrhea, weakness, swelling, nausea, shortness of breath, itchiness, and heart burn. Other side effects may include arrhythmias, QT prolongation, bleeding, and interstitial nephritis. Safety in pregnancy is unclear, with evidence of harm in other animals. It is an antithrombotic. Once started, suddenly stopping anagrelide may cause a rebound rise in platelets and increase risk of blood clots. Monitoring of the platelet count is recommended with any withdrawal of the drug.

Anagrelide was approved for medical use in the United States in 1997 and Europe in 2004. It is available as a generic medication. In the United Kingdom 100 pills of 500 micrograms costs the NHS about £400 as of 2021. This amount in the United States costs about 52 USD.