User:Mr. Ibrahem/Angiomyolipoma

Angiomyolipoma (AML) is a benign tumor of fat, blood vessels, and muscle tissue, that is usually found in the kidney. They rarely cause symptoms, but may occasionally result in blood in the urine or grow to a size that pain occurs. Complications can include hemorrhagic shock and kidney failure. Occasionally other organs like the liver may be affected.

They occur in up to 90% of cases of tuberous sclerosis (TSC) and 50% of cases of lymphangioleiomyomatosis (LAM). In tuberous sclerosis often multiple lesions are present. They may also occur spontaneously. They can usually be diagnosed by CT scan or MRI.

Small angiomyolipoma that do not result in symptoms can often we simple watched. Larger or symptomatic cases may be treated by surgical removal, embolisation, or ablation. In cases due to TSC or LAM, mTOR inhibitors may be an option. Occasionally dialysis or kidney transplant is required. They are uncommon. Females are more commonly affected than males. Onset is generally between 20 and 50 years of age. It was first described in 1900.