User:Mr. Ibrahem/Aortoiliac occlusive disease

Aortoiliac occlusive disease (AIOD) is the blockage of the abdominal aorta or iliac arteries. Symptoms include buttock and thigh pain with exercise and sexual dysfunction. As the disease progresses pain at rest and tissue loss may occur. Complications may include gangrene and amputation.

It generally occurs due to atherosclerosis, with other potential causes including trauma, radiation therapy, and iliac artery endofibrosis. Risk factors include diabetes, high blood pressure, high cholesterol, smoking, and vasculitis. An ankle-brachial index of less than 0.9 supports the diagnosis; which can be confirmed by CT angiography. It is a type of peripheral artery disease.

For cases of gradual onsets managing risk factors is important. Either aspirin or clopidogrel is often used. Surgical options may include endovascular or open repair. Cilostazol may be used despite surgery. Up to a third of people have long term complications post surgery.

How commonly it occurs is unclear; though it is relatively common among people with peripheral artery disease. It occurs more commonly in males and older people. The condition was first described by Robert Graham in 1814.