User:Mr. Ibrahem/Apomorphine

Apomorphine, sold under the brand name Apokyn among others, is a medication used to treat Parkinson's disease. Specifically it is used for "off" episodes which may be seen in advanced disease. It was previously used to bring about vomiting in overdoses. It is given by injection under the skin or into a vein. Onset is generally within 20 minutes and it lasts about an hour.

Common side effects include nausea. Other side effects may include low blood pressure, anxiety, confusion, dizziness, psychosis, vivid dreams, QT prolongation, and trouble sleeping. Use in pregnancy may harm the baby. It should not be used with 5HT 3 antagonists such as ondansetron. It is a dopamine agonist which activates D2, D3, and D5 receptors in the brain.

Apomorphine was approved for medical use in the United States in 2004; however, it was previously used in Europe. In the United Kingdom 5 units of 30 mg costs the NHS about £125 as of 2021. This amount in the United States costs about 6,500 USD.