User:Mr. Ibrahem/Asenapine

Asenapine, sold under the brand name Saphris among others, is an atypical antipsychotic used to treat schizophrenia and mania in bipolar disorder. Use in older people with dementia related psychosis may increase the risk of death. It is used under the tongue.

Common side effects include sleepiness, dizziness, weight gain, movement disorders, and numbness within the mouth. Other side effects may include stroke, neuroleptic malignant syndrome, tardive dyskinesia, diabetes, low white blood cells, seizures, and QT prolongation. How it works is not clear, but is believed to involve blocking serotonin and dopamine receptors.

Asenapine was approved for medical use in the United States in 2009 and Europe in 2010. The first generic versions were approved in 2020. In the United Kingdom it costs the NHS about £100 per month as of 2021. This amount in the United States is about 200 USD.