User:Mr. Ibrahem/Asfotase alfa

Asfotase alfa, sold under the brand name Strensiq, is a medication used to treat hypophosphatasia (HPP) that starts in children. It is given by injection under the skin.

Common side effects include headache, redness of the skin, pain in the limbs, fever, lipodystrophy, allergic reactions, and bruising at the site of injection. Other side effects may include calcification of the eyes or kidneys. Safety in pregnancy is unclear. It is a tissue non-specific alkaline phosphatase (ALP) and it works by replacing this enzyme in those affected.

Asfotase alfa was approved for medical use in the United States and Europe in 2015. In the United Kingdom 4 weeks at a dose of 80 mg costs the NHS about £56,500 as of 2021. This amount in the United States costs about 70,200 USD.