User:Mr. Ibrahem/Avacopan

Avacopan, sold under the brand name Tavneos, is a medication used to treat anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis. This includes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It is taken by mouth.

Common side effects include nausea, headache, low white blood cells, upper respiratory tract infection, diarrhea, vomiting, and inflammation of the nose and throat. Other side effects may include liver problems, allergic reactions, and infections. Safety is unclear in pregnancy. It is a complement 5a receptor (C5aR) antagonist.

Avacopan was approved for medical use in Japan and United States in 2021, and Europe in 2022. In the United Kingdom a month of medication costs the NHS about £5500 as of 2022. This amount in the United States costs about 14,400 USD.