User:Mr. Ibrahem/Benzylpenicillin

Benzylpenicillin, also known as penicillin G, is an antibiotic used to treat a number of bacterial infections. This includes pneumonia, strep throat, syphilis, necrotizing enterocolitis, diphtheria, gas gangrene, leptospirosis, cellulitis, and tetanus. It is not a first-line agent for pneumococcal meningitis. Benzylpenicillin is given by injection into a vein or muscle. Two long-acting forms, benzathine benzylpenicillin and procaine benzylpenicillin, are available for use by injection into a muscle only.

Side effects include diarrhea, seizures, and allergic reactions including anaphylaxis. When used to treat syphilis or Lyme disease a reaction known as Jarisch–Herxheimer may occur. It is not recommended in those with a history of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications.

Benzylpenicillin was discovered in 1928 by Alexander Fleming, who published its details the following year. It came into commercial use in the early 1940s. It is on the World Health Organization's List of Essential Medicines. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200.