User:Mr. Ibrahem/Bortezomib

Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. This includes multiple myeloma in those who have and have not previously received treatment. It is generally used together with other medications. It is given by injection.

Common side effects include nausea, diarrhea, tiredness, low platelets, fever, numbness, low white blood cells, shortness of breath, rash, and abdominal pain. Other severe side effects include low blood pressure, tumour lysis syndrome, heart failure, and reversible posterior leukoencephalopathy syndrome. It is in the class of medications known as proteasome inhibitor. It works by inhibiting proteasomes, cellular complexes that break down proteins.

Bortezomib was approved for medical use in the United States in 2003 and in Europe in 2004. It is on the World Health Organization's List of Essential Medicines. In the United States it costs US$1,360 per 3.5 mg vial. In the United Kingdom this amount costs the NHS £762 such that a course of treatment is about £12,261 as of 2014.