User:Mr. Ibrahem/Bosutinib

Bosutinib codenamed SKI-606, marketed under the trade name Bosulif, is a medication used to treat chronic myelogenous leukemia (CML). Specifically it is used for cases that are Philadelphia chromosome positive. It is taken by mouth.

Common side effects include diarrhea, rash, nausea, tiredness, liver problems, respiratory tract infection, fever, and headache. Other side effects may include bone marrow suppression, heart damage, swelling, and kidney problems. Use in pregnancy may harm the baby. It is a tyrosine kinase inhibitor that blocks BCR-ABL and src.

Bosutinib was approved for medical use in the United States in 2012 and Europe in 2013. In the United Kingdom 4 weeks of treatment costs the NHS about £3,400 as of 2021. This amount in the United States is about 17,000 USD.