User:Mr. Ibrahem/Brentuximab vedotin

Brentuximab vedotin, sold under the brand name Adcetris, is a medication used to treat Hodgkin lymphoma (HL) and certain non-Hodgkin lymphoma (NHL). Specifically it is used for cases that are CD30 positive. It is given by injection into a vein.

Common side effects include peripheral nerve damage, tiredness, nausea, diarrhea, low white blood cells, fever, hair loss, and mouth inflammation. Other side effects may include anaphylaxis, infections, tumor lysis syndrome, liver problems, lung problems, Stevens-Johnson syndrome, and high blood sugar. Use in pregnancy may harm the baby. It is a monoclonal antibody that binds to CD30 linked to the cytotoxin monomethyl auristatin E.

Brentuximab vedotin was approved for medical use in the United States in 2011 and Europe 2012. In the United Kingdom a 50 mg vial costs about £2,500 as of 2021. In the United States this amount costs about 10,100 USD.