User:Mr. Ibrahem/Carbidopa/levodopa

Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa. It is primarily used to manage the symptoms of Parkinson's disease, but it does not slow down the disease or stop it from getting worse. It is taken by mouth. It can take two to three weeks of treatment before benefits are seen. Each dose then begins working in about ten minutes to two hours with a duration of effect of about five hours.

Common side effects include movement problems and nausea. More serious side effects include depression, low blood pressure with standing, sudden onset of sleepiness, psychosis, and increased risk-taking behavior. Carbidopa prevents the breakdown of levodopa outside the brain. In the brain, levodopa is broken down into dopamine by which it has its effects. Carbidopa also helps prevent some of the nausea which levodopa causes.

It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication and is moderately expensive. The wholesale price in the developing world is about US$1.80 to $3.00 a month. In the United States, a month's supply costs about $50 to $150. In 2020, it was the 364th most commonly prescribed medication in the United States, with more than half a million prescriptions.