User:Mr. Ibrahem/Casimersen

Casimersen, sold under the brand name Amondys 45, is a medication used to treat Duchenne muscular dystrophy (DMD). Specifically it is used in cases that have a mutation of the dystrophin gene that is amenable to exon 45 skipping. It is given by gradual injection into a vein.

Common side effects include upper respiratory tract infections, cough, fever, headache, joint pain, and throat pain. Other side effects may include kidney problems. It is an antisense oligonucleotide of phosphorodiamidate morpholino oligomer (PMO).

Casimersen was approved for medical use in the United States in 2021. It is not approved in either Europe or the United Kingdom. In the United States a year or treatment for a child who weights 10 kg is about 264,000 USD as of 2022.