User:Mr. Ibrahem/Ceftolozane/tazobactam

Ceftolozane/tazobactam, sold under the brand name Zerbaxa, is a combination antibiotic used to treat complicated urinary tract infections, hospital acquired pneumonia, and complicated intra-abdominal infections. For intra-abdominal infections it is used together with metronidazole. It is given by injection into a vein.

Common side effects include nausea, headache, constipation, diarrhea, and fever. Other side effects may include anaphylaxis and Clostridioides difficile infection. Ceftolozane is a cephalosporin, which disrupts the bacterial cell wall, while tazobactam blocks the activity of β-lactamase, which protects ceftolozane from degradation.

The combination was approved for medical use in the United States in 2014 and Europe in 2015. It is on the World Health Organization's List of Essential Medicines. In the United Kingdom 10 doses of 1.5 grams costs the NHS about £670 as of 2021. In the United States this amount is about 1,300 USD.