User:Mr. Ibrahem/Chlorambucil

Chlorambucil, sold under the brand name Leukeran among others, is a chemotherapy medication used to treat chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, and non-Hodgkin lymphoma. For CLL it is a preferred treatment. It is given by mouth.

Common side effects include bone marrow suppression. Other serious side effects include an increased long term risk of further cancer, infertility, and allergic reactions. Use during pregnancy often results in harm to the baby. Chlorambucil is in the alkylating agent family of medications. It works by blocking the formation of DNA and RNA.

Chlorambucil was approved for medical use in the United States in 1957. It is on the World Health Organization's List of Essential Medicines. The wholesale cost in the developing world is about US$111.87 per month. In the United Kingdom it costs the NHS about £145.84 per month. It was originally made from nitrogen mustard.