User:Mr. Ibrahem/Clofazimine

Clofazimine, sold under the brand name Lamprene, is a medication used together with rifampicin and dapsone to treat leprosy. It is specifically used for multibacillary (MB) leprosy and erythema nodosum leprosum. Evidence is insufficient to support its use in other conditions. It is taken by mouth.

Common side effects include abdominal pain, diarrhea, itchiness, dry skin, and change in color of the skin. May also cause swelling of the lining of the gastrointestinal tract, increased blood sugar, and sensitivity to the sun. It is unclear if use during pregnancy is safe. Clofazimine is a phenazine dye and believed to work by interfering with DNA.

Clofazimine was discovered in the 1950s at Trinity College, Dublin, and approved for medical use in the United States in 1986. It is on the World Health Organization's List of Essential Medicines. The wholesale cost in the developing world is about US$24 per month. In the United States it is not available commercially but can be obtained from the US Department of Health and Human Services.