User:Mr. Ibrahem/Cobimetinib

Cobimetinib, sold under the brand name Cotellic among others, is a medication used to treat melanoma. Specifically it is used for advanced disease with either BRAF V600E or V600K mutation. It is used together with vemurafenib. Use is not recommended in the United Kingdom. It is taken by mouth.

Common side effects include diarrhea, rash, nausea, fever, sunburns, liver problems, or muscle damage. Other side effects may include bleeding, heart damage, and retinal vein occlusion. Use during pregnancy may harm the baby. It is a MEK inhibitor.

Cobimetinib was approved for medical use in the United States and Europe in 2015. In the United Kingdom treatment for 4 weeks costs the NHS about £4,275 as of 2021. This amount in the United States is about 7,300 USD.