User:Mr. Ibrahem/Conivaptan

Conivaptan, sold under the brand name Vaprisol, is a medication used to treat low sodium in those who either have normal or high total body fluid. While it may improve lab values, it is unclear if it improves outcomes. It is given by injection into a vein.

Common side effects include pain at the site of injection, fever, low potassium, headache, and low blood pressure with standing. Other side effects may include osmotic demyelination syndrome if sodium is corrected too rapidly. Safety in pregnancy is unclear as is safety in heart failure. It is a vasopressin receptor antagonist.

Conivaptan was approved for medical use in the United States in 2005. It has not been approved in the United Kingdom as of 2011. In the United States it costs nearly 1,000 USD per 20 mg dose as of 2022.