User:Mr. Ibrahem/Crofelemer

Crofelemer, sold under the brand name Mytesi, is a medication used to treat diarrhea in people on treatment for HIV. It should not be used for cases due to infection. It is taken by mouth.

Side effects are generally mild. They may include intestinal gas, nausea, constipation, and cough. Safety in pregnancy is unclear. It is believed to work by blocking cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels in the intestines.

Crofelemer was approved for medical use in the United States in 2012. In the United States it costs about 2,400 USD per month as of 2022. It is made from the sap of the South American plant Croton lechleri.