User:Mr. Ibrahem/De Quervain syndrome

De Quervain syndrome is inflammation of two tendons that control movement of the thumb and their tendon sheath. This results in pain at the outside of the wrist. Pain is typically increased with gripping or rotating the wrist. The thumb may also be difficult to move smoothly. Onset of symptoms is gradual.

Risk factors include certain repetitive movements, pregnancy, trauma, and rheumatic diseases. The diagnosis is generally based on symptoms and physical examination. Diagnosis is supported if pain increases when the wrist is bent inwards while a person is grabbing their thumb within a fist.

Treatment involves avoiding activities that bring on the symptoms, pain medications such as NSAIDs, and splinting the thumb. If this is not effective steroid injections or surgery may be recommended. The condition affects about 0.5% of males and 1.3% of females. Those who are middle aged are most often affected. It was first described in 1895 by Fritz de Quervain.