User:Mr. Ibrahem/Desipramine

Desipramine, sold under the brand name Norpramin among others, is a tricyclic antidepressant (TCA) used to treat depression, panic disorder, and postherpetic neuralgia. While benefits may be seen within 5 days, up to 3 weeks may be required for full effects.

Common side effects include dry mouth, constipation, blurry vision, low blood pressure with standing, sleepiness, and weakness. Other side effects may include suicide, mania, arrythmias, and seizures. Safety in pregnancy is unclear. How it works is unclear, but is believed to involve effects on serotonin and norepinephrine.

Desipramine was approved for medical use in the United States in 1964. It is available as a generic medication. In the United States 30 tablets of 100 mg costs about 25 USD as of 2021. It has been widely used.