User:Mr. Ibrahem/Diclofenac/misoprostol

Diclofenac/misoprostol, sold under the brand name Arthrotec, is a combination medication used to treat rheumatoid arthritis or osteoarthritis in those at high risk of NSAID-induced gastroduodenal ulceration. It is taken by mouth.

Common side effects include abdominal pain, diarrhea, nausea, gastritis, dizziness, and low red blood cells. Other side effects may include liver problems, high blood pressure, heart failure, kidney problems, anaphylaxis, and worsening asthma. Use in pregnancy may harm the baby or result in abortion. It contains diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID) and misoprostol a gastrointestinal (GI) protective prostaglandin E1.

The combination was approved for medical use in the United States in 1997. It is available as a generic medication. In the United States 60 tablets costs about 40 USD as of 2023. In the United Kingdom 60 tablets costs the NHS about £12 as of 2021.