User:Mr. Ibrahem/Diclofenamide

Diclofenamide, also known as dichlorphenamide, is a medication used to treat hyperkalemic periodic paralysis and hypokalemic periodic paralysis. Evidence of benefit; however, is weak. It is taken by mouth. It has previously been used to treat glaucoma.

Common side effects include numbness, change in taste, and confusion. Other side effects may include anaphylaxis, low potassium, metabolic acidosis, and falls. Safety in pregnancy is unclear. It is a carbonic anhydrase inhibitor.

Diclofenamide was approved for medical use in the United States in 1958. They; however, were not approved for periodic paralysis until 2016. It was granted orphan medicine status in Europe in 2016; however the request for approval was withdrawn in 2019. In the United States 100 tablets of 50 mg costs about 26,000 USD as of 2021.