User:Mr. Ibrahem/Dornase alfa

Dornase alfa, sold under the brand name Pulmozyme, is a medication used to treat cystic fibrosis. It is used to decrease the thickness of mucus and thus make it easier to cough out. It is used by breathing it in.

Common side effects include change in voice, rash, throat inflammation, chest pain, runny nose, fever, and shortness of breath. While there is no evidence of harm in pregnancy, such use has not been well studied. It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which breaks up DNA outside the cell.

Dornase alfa was approved for medical use in the United States in 1993. In the United Kingdom a month of medication costs the NHS about £500 as of 2021. In the United States this amount costs about 3,400 USD.