User:Mr. Ibrahem/Drospirenone/estetrol

Drospirenone/estetrol, sold under the brand name Nextstellis among others, is a combination medication used by women to prevent pregnancy. Effectiveness is less in those with a BMI of over 30 kg/m2. It is taken by mouth.

Common side effects include irregular vaginal bleeding, mood changes, headaches, breast pain, acne, increased weight, and decreased sex drive. Serious side effects may include blood clots, high potassium, and gallbladder disease. There is no evidence that use in pregnancy harms the baby, though it should be stopped once pregnancy occurs. It contains drospirenone, a progestin, and estetrol, an estrogen.

The combination was approved for medical use in Canada, Europe, and the United States in 2021. In the United States it costs about 200 USD per month. In the United Kingdom this amount costs the NHS about £9.