User:Mr. Ibrahem/Entacapone

Entacapone, sold under the brand name Comtan among others, is a medication used to treat Parkinson's disease. It is used to prevent the wearing off of levodopa/carbidopa before the next dose is due. It is taken by mouth.

Common side effects include uncontrollable movements, nausea, and change in urine color. Other side effects may include abdominal pain, urge to gamble, falling asleep, prostate cancer, low blood pressure with standing, and hallucinations. It works by blocking the enzyme that breaks down levodopa, catechol-O-methyltransferase (COMT).

Entacapone was approved for medical use in Europe in 1998 and the United States in 1999. It is available as a generic medication. In the United Kingdom 100 tablets of 200 mg costs the NHS about £16 as of 2021. This amount in the United States costs about 40 USD.