User:Mr. Ibrahem/Etanercept

Etanercept, sold under the brand name Enbrel among others, is a medication used to treat autoimmune diseases including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, plaque psoriasis, and ankylosing spondylitis. It is given by injection under the skin.

Common side effects include pain at the site of injection and infections. Other side effects may include cancers, heart failure, demyelinating diseases, allergic reactions, and pancytopenia. Safety in pregnancy is unclear. It is a TNF inhibitor which blocks tumor necrosis factor (TNF). It a monoclonal antibody made by recombinant DNA techniques.

Etanercept was approved for medical use in the United States in 1998 and Europe in 2000. It is on the World Health Organization's List of Essential Medicines as an alternative to adalimumab. In the United Kingdom 4 weeks of medication costs the NHS about £715 as of 2021. This amount in the United States costs about 5,700 USD.