User:Mr. Ibrahem/Everolimus

Everolimus is a medication used to prevent rejection after an organ transplant and to treat certain types of cancer. This includes after kidney, heart, and liver transplant. It may be used for breast, kidney, and neuroendocrine tumors. It is taken by mouth.

Common side effects include mouth inflammation, respiratory tract infection, tiredness, vomiting, and diarrhea. Other side effects may include hair loss, low white blood cells, bleeding, kidney problems, blood clotting, and heart failure. It is likely that use during pregnancy would harm the baby. It is a derivative of sirolimus and works similarly; by blocking mammalian target of rapamycin (mTOR).

Everolimus was approved for medical use in the United States and Europe in 2009. It is available as a generic medication. It is on the World Health Organization's List of Essential Medicines. In the United Kingdom a month of treatment post transplant costs about £450 while for certain types of cancer can be £2,900 as of 2020. A similar amount to prevent transplant rejection costs about 450 USD in the United States as of 2021. A generic version was approved in 2021 in the USA.