User:Mr. Ibrahem/Flumazenil

Flumazenil, sold under the brand name Anexate, is a medication used to reverse the effects of benzodiazepines. Routine use is not recommended in those with a decreased level of consciousness. It is given by injection into a vein. Effects begin within 2 minutes and may last for up to 90 minutes.

Common side effects include sweating, blurry vision, headache, and dizziness. Other side effects may include seizures and benzodiazepine withdrawal, especially in people with benzodiazepine dependence. Panic attacks may also occur. Safety in pregnancy is unclear. It works by blocking benzodiazepines at the GABA receptor.

Flumazenil was characterized in 1981, and approved for medical use in the United States in 1991. It is available as a generic medication. In the United Kingdom 0.5 mg cost the NHS about £13 as of 2021. This amount in the United States is about 10 USD.