User:Mr. Ibrahem/Flutamide

Flutamide, sold under the brand name Eulexin among others, is a medication primarily used to treat prostate cancer. For prostate cancer it is used together with a luteinizing hormone-releasing hormone (LHRH). It is also used for unwanted hair growth and hair loss in polycystic ovarian syndrome. It is taken by mouth three times per day.

Common side effects in men include hot flashes, sexual dysfunction, breast enlargement, and nausea. In women, it is generally better tolerated with only dry skin being common. Other side effects may include liver problems, QT prolongation, and sunburns. Use in pregnancy may harm the baby. It is a nonsteroidal antiandrogen (NSA) that works by selectively blocking the androgen receptor (AR).

Flutamide was described in 1967 and was introduced for medical use in 1983. It was approved in the United States in 1989. It is on the World Health Organization's List of Essential Medicines, as an alternative to bicalutamide. It is available as a generic medication. In the United Kingdom 4 weeks of medication costs the NHS about £110 as of 2021. This amount in the United States costs about 85 USD. Use has frequently been replaced by others NSAAs, namely bicalutamide, as it works better, has less side effects, and is easier to take.