User:Mr. Ibrahem/Fluticasone/salmeterol

Fluticasone/salmeterol, sold under the brand name Advair among others, is a combination medication containing fluticasone propionate and salmeterol. It is used in the management of asthma and chronic obstructive pulmonary disease (COPD). It is used by inhaling the medication into the lungs.

Common side effects include thrush, headache, and cough. Serious side effects may include worsening asthma, anaphylaxis, seizures, and heart problems. Safety in pregnancy and breastfeeding is unclear. Fluticasone, a corticosteroid, works by decreasing inflammation while salmeterol, a long-acting beta-adrenoceptor agonist (LABA), works by activating beta-2 adrenergic receptors.

The combination was approved for medical use in the United States in 2000. A generic version was approved in the United States in 2019. A two month supply in the United Kingdom costs the National Health Service about £35 per month as of 2019. In the United States the wholesale cost of this amount is about 89 USD. In 2019, it was the 80th most commonly prescribed medication in the United States, with more than 9million prescriptions.