User:Mr. Ibrahem/Goserelin

Goserelin, sold under the brand name Zoladex among others, is a medication used to treat prostate cancer, breast cancer, endometriosis, dysfunctional uterine bleeding, and uterine fibroids. In prostate cancer it may be used instead of testicle removal. It is given by injection under the skin.

Common side effects include hot flushes, sexual dysfunction, depression, and pain. Other side effects may include pituitary apoplexy, QT prolongation, osteoporosis, and anaphylaxis. > Use in pregnancy may harm the baby. It is a gonadotropin releasing hormone agonist (GnRH agonist) which results in decreased follicle stimulating hormone (FSH) and luteinising hormone (LH) followed by decreased androgen and estrogen.

Goserelin was patented in 1976 and approved for medical use in 1987. It is on the World Health Organization's List of Essential Medicines as an alternative to leuprorelin. In the United Kingdom a 3.6 mg implant costs the NHS about £70 as of 2021. This amount in the United States is about 600 USD.