User:Mr. Ibrahem/HPV vaccine

Human papillomavirus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus. It is estimated that the vaccines may prevent 70% of cervical cancer, 80% of anal cancer, 60% of vaginal cancer, 40% of vulvar cancer and possibly some mouth cancer. They additionally prevent some genital warts, with the quadrivalent and nonavalent vaccines that protect against HPV types HPV-6 and HPV-11 providing greater protection.

The World Health Organization (WHO) recommends HPV vaccines as part of routine vaccinations in all countries, along with other prevention measures. The vaccines require two or three doses depending on a person's age and immune status. Vaccinating girls around the ages of nine to thirteen is typically recommended. The vaccines provide protection for at least 5 to 10 years. Cervical cancer screening is still required following vaccination. Vaccinating a large portion of the population may also benefit the unvaccinated. In those already infected, the vaccines are not effective.

HPV vaccines are very safe. Pain at the site of injection occurs in about 80% of people. Redness and swelling at the site and fever may also occur. No link to Guillain–Barré syndrome has been found. Available vaccines protect against either two, four, or nine types of HPV. All protect against at least HPV types 16 and 18, which are associated with the greatest risk of cervical cancer.

The first HPV vaccine became available in 2006. As of 2018, 80 countries include it in their routine vaccinations, at least for girls. It is on the World Health Organization's List of Essential Medicines. The wholesale cost in the developing world is about US$47 a dose as of 2014. In the United States, it costs more than US$200. Vaccination may be cost effective in the developing world. As of 2017, Gardasil 9 is the only version available in the United States.