User:Mr. Ibrahem/Hepatitis B vaccine

Hepatitis B vaccine is a vaccine that prevents hepatitis B. It is given by injection, usually into muscle, but can be given under the skin in people with bleeding disorders. In healthy people routine immunization results in more than 95% of people being protected. Blood testing to verify that the vaccine has worked is recommended in those at high risk.

The first dose is recommended within 24 hours of birth with either two or three more doses given after that. This includes in those with poor immune function such as from HIV/AIDS and those born premature. It is also recommended that health-care workers be vaccinated. Additional doses may be needed in people with poor immune function but are not necessary for most people. In those who have been exposed to the hepatitis B virus (HBV) but not immunized, hepatitis B immune globulin should be given in addition to the vaccine.

Serious side effects from the hepatitis B vaccine are very uncommon. Pain may occur at the site of injection. It is safe for use during pregnancy or while breastfeeding. It has not been linked to Guillain–Barré syndrome. The hepatitis B vaccines are produced with recombinant DNA techniques. They are available both by themselves and in combination with other vaccines.

The first hepatitis B vaccine was approved in the United States in 1981. It has been available since 1982. A recombinant version came to market in 1986. It is on the World Health Organization's List of Essential Medicines. , the wholesale cost in the developing world is US$0.58–13.20 per dose. In the United States it costs US$50–100.