User:Mr. Ibrahem/Histrelin

Histrelin, sold under the brand names Vantas among others, is a medication used to treat advanced prostate cancer. It may also be used for precocious puberty and in transgender children. It is given by injection under the skin.

Common side effects include pain at the site of injection, hot flashes, breast enlargement, sexual dysfunction, tiredness, kidney problems, constipation, weight loss, and trouble sleeping. Other side effects may include osteoporosis, high blood sugar, liver problems, anaphylaxis, and pituitary apoplexy. Use in pregnancy may harm the baby. It acts similar to gonadotropin-releasing hormone (GnRH), resulting in increased luteinizing hormone (LH) and follicle stimulating hormone (FSH), and therefore decreased testosterone and estrogen.

Histrelin was approved for medical use in the United States in 1991. It is available as a generic medication. In the United States an implant costs about 5,100 USD per year as of 2021. Since 2014 it is no longer commercially available in the United Kingdom.