User:Mr. Ibrahem/Idursulfase

Idursulfase, sold under the brand name Elaprase, is a medication used to treat mucopolysaccharidosis II (MPS-II, Hunter syndrome). It is given by gradual injection into a vein. It is used long term. Effects on life expectancy and quality of life is unclear.

Common side effects include rash, fever, headache, high blood pressure, and flushing. Other side effects may include shortness of breath, heartburn, chest pain, and anaphylaxis. It is a form of lysosomal enzyme known as iduronate-2-sulfatase and is made by recombinant DNA technology.

Idursulfase was approved for medical use in the United States in 2006 and Europe in 2007. In the United States it costs about 475,000 USD to treat a 35 kg person for a year. In the United Kingdom this amount costs £310,000.