User:Mr. Ibrahem/Ingenol mebutate

Ingenol mebutate, sold under the brand name Picato, is a medication used to treat actinic keratosis. It is applied to the skin once per day for 2 to 3 days. It appears to work the same as fluorouracil or imiquimod.

Common side effects include redness, skin peeling, blistering, and itchiness. Other side effects may include skin cancer in an extra 4% of people, allergic reactions, and shingles. Safety in pregnancy is unclear. It is a macrocyclic diterpene ester.

Ingenol mebutate was approved for medical use in the United States in 2012. While it was approved in Europe in 2012, it was subsequently withdrawn due to concerns regarding side effects. In the United States three doses costs about 1,100 USD as of 2021. It from the sap of the milkweed plant.