User:Mr. Ibrahem/Inotersen

Inotersen, sold under the brand name Tegsedi, is a medication used to treat nerve damage in hereditary transthyretin-mediated amyloidosis (hATTR). It is used in people who are still able to walk. It is given by injection under the skin.

Common side effects redness and pain at the site of injection, nausea, headache, tiredness, low platelets, and fever. Other side effects may include kidney inflammation, stroke, vitamin A deficiency, allergic reactions, and liver problems. It is a antisense oligonucleotide.

Inotersen was approved for medical use in the United States and Europe in 2018. In the United Kingdom it costs the NHS about £332,000 per year as of 2021. In the United States this amount costs about 521,000 USD while in Canada it is about 420,000 CAD.