User:Mr. Ibrahem/Insulin lispro

Insulin lispro, sold under the brand name Humalog among others, is a type of insulin used to treat type 1 and type 2 diabetes. Typically it is taken around the time of eating. It is used by injection under the skin or within an insulin pump. Onset of effects typically occurs within 30 minutes and lasts about 5 hours. Often a longer acting insulin like NPH is also needed.

Common side effects include low blood sugar. Other serious side effects may include low blood potassium. Use in pregnancy and breastfeeding is generally safe. It works the same as human insulin by increasing the amount of glucose that tissues take in and decreasing the amount of glucose made by the liver.

Insulin lispro was first approved for use in the United States in 1996. It is a manufactured form of human insulin where an amino acid has been switched. In the United Kingdom it costs the NHS about GB£19 per 1000 units as of 2019. In the United States the wholesale cost of this amount is about US$300. In 2024 the price had decreased to about US$20. In 2017, it was the 124th most commonly prescribed medication in the United States, with more than six million prescriptions.