User:Mr. Ibrahem/Kidney agenesis

Kidney agenesis is a birth defect in which one or both kidneys fail to develop. If only one kidney is involved, many people have no symptoms, though some develop high blood pressure and kidney failure. If both kidneys are absent, the lungs will fail to develop and the child will die shortly after birth.

A number of genetic mutations, such as in the RET proto-oncogene, can result in the condition. Some cases run in families in either an autosomal dominant or autosomal recessive pattern. Other risk factors include diabetes and the use of certain medication during pregnancy. Diagnosis may occur before or after birth via medical imaging.

Among those with a single kidney, regular monitoring of kidney function and blood pressure is recommended. If high blood pressure is present ACE inhibitors may be recommended. About 1 in 2,000 people have a single kidney affected and about 1 in 8,500 have both kidneys are affected. Both kidneys are affected more often in males than females.