User:Mr. Ibrahem/Lamivudine/tenofovir

Lamivudine/tenofovir disoproxil (3TC/TDF), sold under the brand name Cimduo among others, is a combination medication used to prevent and treat HIV/AIDS. It is taken by mouth. It is used together with other medications in people weighing more than 35 kg.

Common side effects include headache, pain, diarrhea, rash, and depression. Other side effects may include liver problems, kidney problems, pancreatitis, osteoporosis, lactic acidosis, and immune reconstitution syndrome. In those who are also infected with hepatitis B, stopping use may worsen outcomes. It contains lamivudine (3TC) and tenofovir disoproxil fumarate (TDF) both reverse transcriptase inhibitors.

The combination was approved for medical use in the United States in 2018. It is also approved in a number of countries in Europe. The lamivudine component was first approved in 1995. It was added to the World Health Organization's List of Essential Medicines in 2021. It is available in some areas as a generic medication. In the United States it costs about 1,100 USD per month as of 2023. Though the individual components cost about 140 USD per month if purchased separately. It appears to work as well as emtricitabine/tenofovir but is less expensive.