User:Mr. Ibrahem/Ledipasvir/sofosbuvir

Ledipasvir/sofosbuvir, sold under the trade name Harvoni among others, is a medication used to treat hepatitis C. It is a fixed-dose combination of ledipasvir and sofosbuvir. Cure rates are 94% to 99% in people infected with hepatitis C virus (HCV) genotype 1. Some evidence also supports use in HCV genotype 3 and 4. It is taken daily by mouth for 8–24 weeks.

It is generally well tolerated. Common side effects include muscle pains, headache, nausea, rash, and cough. It is unclear if use in pregnancy is safe for the baby. Ledipasvir works by decreasing the activity of NS5A and sofosbuvir works by decreasing the activity of NS5B polymerase.

Ledipasvir/sofosbuvir was approved for medical use in the United States in 2014. It is on the World Health Organization's List of Essential Medicines. The wholesale cost in the United States is about US$91,589.40 for 12 weeks as of 2016. In Bangladesh this amount costs US$1,092.00. Some people travel to India to get access to lower cost medication.