User:Mr. Ibrahem/Leflunomide

Leflunomide, sold under the brand name Arava among others, is a medication used to treat rheumatoid arthritis and psoriatic arthritis and to prevent rejection following organ transplantation. It is taken by mouth. Onset is generally within 6 weeks.

Common side effects include diarrhea, liver inflammation, hair loss, and rash. Other side effects may include infections, low platelets, low white blood cells, and cancer. Use during pregnancy may harm the baby. It is an disease-modifying antirheumatic drug (DMARD) and immunosuppressant. It works by blocking dihydroorotate dehydrogenase which decreases lymphocytes.

Leflunomide was approved for medical use in the United States in 1998 and Europe in 1999. It is available as a generic medication. In the United Kingdom it costs the NHS about £5 as of 2021. In the United States this amount costs about 100 USD.