User:Mr. Ibrahem/Levomepromazine

Levomepromazine, also known as methotrimeprazine, is a medication used for schizophrenia and palliative care. In palliative care it is used for restlessness, pain, and vomiting. It may be used by mouth or by injection. Effects generally begin around 0.5 to 3 hours and last for 8 hours.

Side effects may include low blood pressure with standing, sleepiness, dry mouth, liver problems, and dystonia. Serious side effect may include priapism, QT prolongation, and neuroleptic malignant syndrome. It is an antipsychotic of the phenothiazine type. It works by blocking a variety of receptors, including adrenergic, dopamine, histamine, muscarinic acetylcholine, and serotonin.

Levomepromazine was patented in 1954 and come into medical use in the United State in 1957. It is available as a generic medication. In the United Kingdom 84 tablets of 25 mg costs the NHS about £20 as of 2020. It has been widely used; though is no longer commercially available in the United States.